Total flavonoids from Semen Cuscutae target MMP9 and promote invasion of EVT cells via Notch/AKT/MAPK signaling pathways

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Feixia Gao; Chun Zhou; Weiyu Qiu; Haiwang Wu; Jing Li; Jinting Peng; Min Qiu; Chun Liang; Jie Gao; Songping Luo;

Abstract Miscarriage is a common condition during pregnancy and its mechanisms remain largely unknown. Extravillous trophoblast (EVT) cell invasion is required to maintain normal pregnancy and its malfunction has been proposed as a major cause for miscarriage. Homeostas... View more
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