publication . Article . Other literature type . 2017

Probiotic Mixture Golden Bifido Prevents Neonatal Escherichia coli K1 Translocation via Enhancing Intestinal Defense

Qing Zeng; Xiaolong He; Santhosh Puthiyakunnon; Hansen Xiao; Zelong Gong; Swapna Boddu; Lecheng Chen; Huiwen Tian; Huiwen Tian; Sheng-He Huang; ...
Open Access English
  • Published: 20 Sep 2017 Journal: Frontiers in Microbiology, volume 8 (eissn: 1664-302X, Copyright policy)
  • Publisher: Frontiers Media S.A.
Abstract
Escherichia coli (E. coli) K1 sepsis and meningitis is a severe infection characterized by high mortality in neonates. Successful colonization and translocation across the intestinal mucosa have been regarded as the critical steps for E. coli K1 sepsis and meningitis. We recently reported that the probiotic mixture, Golden Bifido (containing live Lactobacillus bulgaricus, Bifidobacterium, and Streptococcus thermophilus, LBS) has a preventive role against neonatal E. coli K1 bacteremia and meningitis. However, the interaction between the neonatal gut barrier, probiotics and E. coli K1 is still not elucidated. The present study aims to investigate how LBS exerts i...
Subjects
free text keywords: Microbiology, Original Research, probiotics, intestinal barrier, bacterial translocation, neonatal sepsis and meningitis, mucin, tight junction, QR1-502, Intestinal permeability, medicine.disease, medicine, Immunoglobulin A, biology.protein, biology, Sepsis, Escherichia coli, medicine.disease_cause, Lactobacillus, biology.organism_classification, Bifidobacterium, Probiotic, law.invention, law, Immunology
55 references, page 1 of 4

Bauer T. M.Fernández J.Navasa M.Vila J.Rodés J. (2002). Failure of Lactobacillus spp. to prevent bacterial translocation in a rat model of experimental cirrhosis. J. Hepatol. 36 501–506. 10.1016/S0168-8278(02)00003-X 11943421 [PubMed] [DOI]

Bhagat R.Hussain S. Q.Gattoo I. A.Wani S. A. (2015). Incidence of meningitis in late onset sepsis. Int. J. Contemp. Pediatr. 2 96–102. 10.5455/2349-3291.ijcp20150507 [OpenAIRE] [DOI]

Birchenough G. M.Johansson M. E.Stabler R. A.Dalgakiran F.Hansson G. C.Wren B. W. (2013). Altered innate defenses in the neonatal gastrointestinal tract in response to colonization by neuropathogenic Escherichia coli. Infect. Immun. 81 3264–3275. 10.1128/IAI.00268-13 23798529 [OpenAIRE] [PubMed] [DOI]

Blume C.David J.Bell R. E.Laver J. R.Read R. C.Clark G. C. (2016). Modulation of human airway barrier functions during Burkholderia thailandensis and Francisella tularensis infection running title: airway barrier functions during bacterial infections. Pathogens 5:E53 10.3390/pathogens5030053 [OpenAIRE] [DOI]

Borosmajewska J.Wei X.Milewski S.Williams D. W. (2015). A novel in vitro assay for assessing efficacy and toxicity of antifungals using human leukemic cells infected with Candida albicans. J. Appl. Microbiol. 119 177–187. 10.1111/jam.12817 25845720 [OpenAIRE] [PubMed] [DOI]

Bruewer M.Samarin S.Nusrat A. (2006). Inflammatory bowel disease and the apical junctional complex. Ann. N. Y. Acad. Sci. 1072 242–252. 10.1196/annals.1326.017 17057204 [OpenAIRE] [PubMed] [DOI]

Burns J. L.Griffith A.Barry J. J.Jonas M.Chi E. Y. (2001). Transcytosis of gastrointestinal epithelial cells by Escherichia coli K1. Pediatr. Res. 49 30–37. 10.1203/00006450-200101000-00010 11134488 [OpenAIRE] [PubMed] [DOI]

Cammarota G.Ianiro G.BibbòS.Gasbarrini A. (2014). Gut microbiota modulation: probiotics, antibiotics or fecal microbiota transplantation? Intern. Emerg. Med. 9 365–373. 10.1007/s11739-014-1069-4 24664520 [OpenAIRE] [PubMed] [DOI]

Cilieborg M. S.Thymann T.Siggers R.Boye M.Bering S. B.Jensen B. B. (2011). The incidence of necrotizing enterocolitis is increased following probiotic administration to preterm pigs. J. Nutr. 141 223–230. 10.3945/jn.110.128561 21178092 [OpenAIRE] [PubMed] [DOI]

Claud E. C. (2009). Neonatal necrotizing enterocolitis –inflammation and intestinal immaturity. Antiinflamm. Antiallergy Agents Med. Chem. 8 248–259. 10.2174/187152309789152020 20498729 [OpenAIRE] [PubMed] [DOI]

Constantinovits M.Sipos F.Molnár B.Tulassay Z.Mûzes G. (2012). Organizer and regulatory role of colonic isolated lymphoid follicles in inflammation. Acta Physiol. Hung. 99 344–352. 10.1556/APhysiol.99.2012.3.11 22982722 [OpenAIRE] [PubMed] [DOI]

Corfield A. P.Carroll D.Myerscough N.Probert C. S. (2001). Mucins in the gastrointestinal tract in health and disease. Front. Biosci. 6 D1321–D1357.11578958 [OpenAIRE] [PubMed]

Deshmukh H. S.Liu Y.Menkiti O. R.Mei J.Dai N.O’leary C. E. (2014). The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice. Nat. Med. 20 524–530. 10.1038/nm.3542 24747744 [OpenAIRE] [PubMed] [DOI]

Fransen F.Zagato E.Mazzini E.Fosso B.Manzari C.El A. S. (2015). BALB/c and C57BL/6 mice differ in polyreactive IgA abundance, which impacts the generation of antigen-specific IgA and microbiota diversity. Immunity 43 527–540. 10.1016/j.immuni.2015.08.011 26362264 [OpenAIRE] [PubMed] [DOI]

Fukuda S.Toh H.Hase K.Oshima K.Nakanishi Y.Yoshimura K. (2011). Bifidobacteria can protect from enteropathogenic infection through production of acetate. Nature 469 543–547. 10.1038/nature09646 21270894 [OpenAIRE] [PubMed] [DOI]

55 references, page 1 of 4
Abstract
Escherichia coli (E. coli) K1 sepsis and meningitis is a severe infection characterized by high mortality in neonates. Successful colonization and translocation across the intestinal mucosa have been regarded as the critical steps for E. coli K1 sepsis and meningitis. We recently reported that the probiotic mixture, Golden Bifido (containing live Lactobacillus bulgaricus, Bifidobacterium, and Streptococcus thermophilus, LBS) has a preventive role against neonatal E. coli K1 bacteremia and meningitis. However, the interaction between the neonatal gut barrier, probiotics and E. coli K1 is still not elucidated. The present study aims to investigate how LBS exerts i...
Subjects
free text keywords: Microbiology, Original Research, probiotics, intestinal barrier, bacterial translocation, neonatal sepsis and meningitis, mucin, tight junction, QR1-502, Intestinal permeability, medicine.disease, medicine, Immunoglobulin A, biology.protein, biology, Sepsis, Escherichia coli, medicine.disease_cause, Lactobacillus, biology.organism_classification, Bifidobacterium, Probiotic, law.invention, law, Immunology
55 references, page 1 of 4

Bauer T. M.Fernández J.Navasa M.Vila J.Rodés J. (2002). Failure of Lactobacillus spp. to prevent bacterial translocation in a rat model of experimental cirrhosis. J. Hepatol. 36 501–506. 10.1016/S0168-8278(02)00003-X 11943421 [PubMed] [DOI]

Bhagat R.Hussain S. Q.Gattoo I. A.Wani S. A. (2015). Incidence of meningitis in late onset sepsis. Int. J. Contemp. Pediatr. 2 96–102. 10.5455/2349-3291.ijcp20150507 [OpenAIRE] [DOI]

Birchenough G. M.Johansson M. E.Stabler R. A.Dalgakiran F.Hansson G. C.Wren B. W. (2013). Altered innate defenses in the neonatal gastrointestinal tract in response to colonization by neuropathogenic Escherichia coli. Infect. Immun. 81 3264–3275. 10.1128/IAI.00268-13 23798529 [OpenAIRE] [PubMed] [DOI]

Blume C.David J.Bell R. E.Laver J. R.Read R. C.Clark G. C. (2016). Modulation of human airway barrier functions during Burkholderia thailandensis and Francisella tularensis infection running title: airway barrier functions during bacterial infections. Pathogens 5:E53 10.3390/pathogens5030053 [OpenAIRE] [DOI]

Borosmajewska J.Wei X.Milewski S.Williams D. W. (2015). A novel in vitro assay for assessing efficacy and toxicity of antifungals using human leukemic cells infected with Candida albicans. J. Appl. Microbiol. 119 177–187. 10.1111/jam.12817 25845720 [OpenAIRE] [PubMed] [DOI]

Bruewer M.Samarin S.Nusrat A. (2006). Inflammatory bowel disease and the apical junctional complex. Ann. N. Y. Acad. Sci. 1072 242–252. 10.1196/annals.1326.017 17057204 [OpenAIRE] [PubMed] [DOI]

Burns J. L.Griffith A.Barry J. J.Jonas M.Chi E. Y. (2001). Transcytosis of gastrointestinal epithelial cells by Escherichia coli K1. Pediatr. Res. 49 30–37. 10.1203/00006450-200101000-00010 11134488 [OpenAIRE] [PubMed] [DOI]

Cammarota G.Ianiro G.BibbòS.Gasbarrini A. (2014). Gut microbiota modulation: probiotics, antibiotics or fecal microbiota transplantation? Intern. Emerg. Med. 9 365–373. 10.1007/s11739-014-1069-4 24664520 [OpenAIRE] [PubMed] [DOI]

Cilieborg M. S.Thymann T.Siggers R.Boye M.Bering S. B.Jensen B. B. (2011). The incidence of necrotizing enterocolitis is increased following probiotic administration to preterm pigs. J. Nutr. 141 223–230. 10.3945/jn.110.128561 21178092 [OpenAIRE] [PubMed] [DOI]

Claud E. C. (2009). Neonatal necrotizing enterocolitis –inflammation and intestinal immaturity. Antiinflamm. Antiallergy Agents Med. Chem. 8 248–259. 10.2174/187152309789152020 20498729 [OpenAIRE] [PubMed] [DOI]

Constantinovits M.Sipos F.Molnár B.Tulassay Z.Mûzes G. (2012). Organizer and regulatory role of colonic isolated lymphoid follicles in inflammation. Acta Physiol. Hung. 99 344–352. 10.1556/APhysiol.99.2012.3.11 22982722 [OpenAIRE] [PubMed] [DOI]

Corfield A. P.Carroll D.Myerscough N.Probert C. S. (2001). Mucins in the gastrointestinal tract in health and disease. Front. Biosci. 6 D1321–D1357.11578958 [OpenAIRE] [PubMed]

Deshmukh H. S.Liu Y.Menkiti O. R.Mei J.Dai N.O’leary C. E. (2014). The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice. Nat. Med. 20 524–530. 10.1038/nm.3542 24747744 [OpenAIRE] [PubMed] [DOI]

Fransen F.Zagato E.Mazzini E.Fosso B.Manzari C.El A. S. (2015). BALB/c and C57BL/6 mice differ in polyreactive IgA abundance, which impacts the generation of antigen-specific IgA and microbiota diversity. Immunity 43 527–540. 10.1016/j.immuni.2015.08.011 26362264 [OpenAIRE] [PubMed] [DOI]

Fukuda S.Toh H.Hase K.Oshima K.Nakanishi Y.Yoshimura K. (2011). Bifidobacteria can protect from enteropathogenic infection through production of acetate. Nature 469 543–547. 10.1038/nature09646 21270894 [OpenAIRE] [PubMed] [DOI]

55 references, page 1 of 4
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publication . Article . Other literature type . 2017

Probiotic Mixture Golden Bifido Prevents Neonatal Escherichia coli K1 Translocation via Enhancing Intestinal Defense

Qing Zeng; Xiaolong He; Santhosh Puthiyakunnon; Hansen Xiao; Zelong Gong; Swapna Boddu; Lecheng Chen; Huiwen Tian; Huiwen Tian; Sheng-He Huang; ...