publication . Article . Other literature type . 2016

Research on the Relationships between Endogenous Biomarkers and Exogenous Toxic Substances of Acute Toxicity in Radix Aconiti.

Zhou, Haonan; Zhang, Pengjie; Hou, Zhiguo; Xie, Jiabin; Wang, Yuming; Yang, Bin; Xu, Yanyan; Li, Yubo;
Open Access
  • Published: 25 Nov 2016 Journal: Molecules, volume 21, page 1,623 (eissn: 1420-3049, Copyright policy)
  • Publisher: MDPI AG
Abstract
Radix Aconiti, a classic traditional Chinese medicine (TCM), has been widely used throughout China for disease treatment due to its various pharmacological activities, such as anti-inflammatory, cardiotonic, and analgesic effects. However, improper use of Radix Aconiti often generated severe acute toxicity. Currently, research on the toxic substances of Radix Aconiti is not rare. In our previous study, acute toxic biomarkers of Radix Aconiti have been found. However, few studies were available to find the relationships between these endogenous biomarkers and exogenous toxic substances. Therefore, in this study, toxic substances of Radix Aconiti have been found u...
Subjects
free text keywords: Acute toxicity, Toxicity, Biomarker (medicine), Medicine, business.industry, business, Radix Aconiti, Correlation test, Traditional Chinese medicine, Endogeny, Pharmacology, Deoxyaconitine, toxic substances, biomarkers, corresponding relationships, Organic chemistry, QD241-441, Article
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