publication . Article . 2016

Examination the expression pattern of HSP70 heat shock protein in chicken PGCs and developing genital ridge

Mahek Anand; Roland Tóth; Alayu Kidane; Alexandra Nagy; Bence Lázár; Eszter Patakiné Várkonyi; Krisztina Liptói; Elen Gocza;
Open Access English
  • Published: 01 May 2016 Journal: Scientific Papers Animal Science and Biotechnologies (issn: 1841-9364, eissn: 2344-4576, Copyright policy)
  • Publisher: Agroprint Timisoara
Abstract
Chicken Primordial Germ cells (PGCs) are emerging pioneers in the field of applied embryology and stem cell technology. Now-a-days transgenic chickens are promising models to study human disease pathophysiology and drug designing. However, most of the molecular mechanism, which govern the stemness and pluripotency of chicken PGCs, not known in details. Recent studies have indicated the role of HSP70 in early embryonic development in many vertebrate species. Exposure of chicken to heat stress result in activation of heat shock factors which activate the transcription of HSP70. Exposure chicken eggs to acute heat stress effects HSP70 expression in PGCs and gonads....
Subjects
Medical Subject Headings: embryonic structuresanimal structuresendocrine systemurogenital system
free text keywords: apoptosis, heat stress, HSP70, genital ridges, PGCs, Agriculture, S, Technology, T, Science, Q
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