publication . Article . 2018

Hepatoprotective effects of hexane root extract of Alchornea laxiflora in sodium arsenate toxicity in wistar albino rats

Esosa Samuel Uhunmwangho; Nurudeen Olajide Rasaq; Iyanuoluwa Olubukola Osikoya;
Open Access English
  • Published: 01 Jan 2018 Journal: CHRISMED Journal of Health and Research, volume 5, issue 1, pages 38-42 (issn: 2348-3334, Copyright policy)
  • Publisher: Wolters Kluwer Medknow Publications
Abstract
Background: Medicinal plants are have been used in the treatment of myriad disease conditions, Alchornea laxiflora is one of such medicinal plant. Aim: To investigate the hepatoprotective effect of hexane root extract of Alchornea laxiflora against sodium arsenate induced liver damage in wistar male rats. Setting and Design: Extraction and administration of bioactive extract. Materials and Methods: Extraction of air-dried ground root of Alchornea laxiflora was done by extracting 500 g with 500 cm of 95% hexane for 72 hrs.The animals (120-150 g) were pre-treated with the extract at varying doses (0.1, 0.5, 1.0, 10, 50 and 100 mg/kg body weight) for seven days ora...
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free text keywords: Alchornea laxiflora, hepatoprotective, liver damage, sodium arsenate, lcsh:Medicine, lcsh:R, lcsh:Nursing, lcsh:RT1-120, Traditional medicine, Medicine, business.industry, business, Toxicant, chemistry.chemical_compound, chemistry, Medicinal plants, Globulin, biology.protein, biology, Albumin, Toxicity, Alkaline phosphatase, Glutathione
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