publication . Article . 2013

EVALUATION OF ULTRASOUND REMISSION CRITERIA IN PATIENTS WITH RHEUMATOID ARTHRITIS DURING TOCILIZUMAB THERAPY

Rita Aleksandrovna Osipyants; D E Karateev; E Yu Panasyuk; G V Lukina; A V Smirnov; S I Glukhova; E N Aleksandrova; A V Volkov; E L Nasonov;
Open Access
  • Published: 01 Dec 2013 Journal: Rheumatology Science and Practice, volume 51, page 500 (issn: 1995-4484, eissn: 1995-4492, Copyright policy)
  • Publisher: Mediar Press
Abstract
Objective: to study the association of ultrasound (US) remission criteria with the clinical and laboratory indicators of inflammatory activity, functional status, and X-ray changes in patients with rheumatoid arthritis (RA) during tocilizumab (TCZ) therapy.Subjects and methods. The trial included 36 patients with RA (meeting the 1987 American College of Rheumatology (ACR) criteria) who had received TCZ for 6 months. The authors made a clinical and laboratory assessment of RA activity (DAS28-CRP, and SDAI), functional impairments (HAQ index) and US verification of wrist joint synovitis (a Voluson-i device, GE, 4-13-MHz linear transducer) at baseline and 6 months ...
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Subjects
free text keywords: rheumatoid arthritis remission, joint ultrasonography, subclinical synovitis, x-ray destruction progression, tocilizumab, Remission criteria, Synovitis, medicine.disease, medicine, Correlation and dependence, Power doppler, Subclinical infection, Surgery, medicine.medical_specialty, Tocilizumab, chemistry.chemical_compound, chemistry, Ultrasound, business.industry, business, Internal medicine, Gastroenterology, Rheumatoid arthritis, lcsh:Diseases of the musculoskeletal system, lcsh:RC925-935
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