publication . Article . 2008

Long-term nifedipine CR therapy and arterial characteristics in hypertensive patients aged over 60 years

V. E. Oleynikov; I. B. Matrosova; E. E. Grishaeva; N. A. Borisova; E. I. Yastrebova;
Open Access Russian
  • Published: 01 Dec 2008 Journal: Кардиоваскулярная терапия и профилактика (issn: 1728-8800, eissn: 2619-0125, Copyright policy)
Aim. To study arterial structure and function in patients aged over 60 years with Stage I-II isolated systolic and systolo-diastolic arterial hypertension (ISAH, SDAH). To assess vasoprotective effects of 24-week treatment with a calcium antagonist nifedipine (Cordaflex® RD).Material and methods. This prospective 24-week study included 48 patients with Stage I-II AH, aged over 60 years. SDAH and ISAH patients were administered Cordaflex® RD (40 mg/d), and treatment effectiveness was assessed by office blood pressure (BP) dynamics. Vasoprotective effects of the medication were assessed by volume sphyg-mography and echocardiography dynamics.Results. Cordaflex® RD ...
free text keywords: nifedipine, isolated systolic and systolo-diastolic arterial hypertension, arterial stiffness, endothelial dysfunction, pulse wave velocity, Diseases of the circulatory (Cardiovascular) system, RC666-701
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