Diagnosis of Food Allergy Based on Oral Food Challenge Test

Article English OPEN
Komei Ito ; Atsuo Urisu (2009)
  • Publisher: Elsevier
  • Journal: Allergology International (issn: 1323-8930)
  • Related identifiers: doi: 10.2332/allergolint.09-RAI-0140
  • Subject: food hypersensitivity | RC581-607 | guideline | immunoglobulin E | Immunologic diseases. Allergy | oral food challenge | tolerance
    mesheuropmc: nervous system | behavioral disciplines and activities | psychological phenomena and processes | digestive, oral, and skin physiology | mental disorders

Diagnosis of food allergy should be based on the observation of allergic symptoms after intake of the suspected food. The oral food challenge test (OFC) is the most reliable clinical procedure for diagnosing food allergy. The OFC is also applied for the diagnosis of tolerance of food allergy. The Japanese Society of Pediatric Allergy and Clinical Immunology issued the 'Japanese Pediatric Guideline for Oral Food Challenge Test in Food Allergy 2009' in April 2009, to provide information on a safe and standardized method for administering the OFC. This review focuses on the clinical applications and procedure for the OFC, based on the Japanese OFC guideline.
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