Crystal Structure of the Substrate-Binding Domain from Listeria monocytogenes Bile-Resistance Determinant BilE

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Stephanie J. Ruiz; Gea K. Schuurman-Wolters; Bert Poolman;
  • Publisher: MDPI AG
  • Journal: Crystals, volume 6, issue 12,page162 (issn: 2073-4352, eissn: 2073-4352)
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  • Identifiers: doi: 10.3390/cryst6120162
  • Subject: Listeria monocytogenes | Crystallography | lmo1421 | lmo1422 | ABC transporters | substrate-binding domain | bile resistance | ABC importers | substrate-binding protein | QD901-999
    mesheuropmc: digestive system

BilE has been reported as a bile resistance determinant that plays an important role in colonization of the gastrointestinal tract by Listeria monocytogenes, the causative agent of listeriosis. The mechanism(s) by which BilE mediates bile resistance are unknown. BilE sh... View more
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