Selector genes display tumor cooperation and inhibition in Drosophila epithelium in a developmental context-dependent manner

Article English OPEN
Ram Prakash Gupta; Anjali Bajpai; Pradip Sinha;
(2017)
  • Publisher: The Company of Biologists
  • Journal: Biology Open,volume 6,issue 11,pages1,581-1,591 (issn: 2046-6390, eissn: 2046-6390)
  • Related identifiers: doi: 10.1242/bio.027821, pmc: PMC5703612
  • Subject: Cooperative tumorigenesis | Q | Research Article | Drosophila | Cell fate | Science | Selector genes | Biology (General) | QH301-705.5
    mesheuropmc: genetic structures | animal structures

ABSTRACT During animal development, selector genes determine identities of body segments and those of individual organs. Selector genes are also misexpressed in cancers, although their contributions to tumor progression per se remain poorly understood. Using a model of ... View more
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