Selector genes display tumor cooperation and inhibition in Drosophila epithelium in a developmental context-dependent manner

Article English OPEN
Gupta, Ram Prakash; Bajpai, Anjali; Sinha, Pradip;
  • Publisher: The Company of Biologists
  • Journal: Biology Open, volume 6, issue 11, pages 1,581-1,591 (issn: 2046-6390, eissn: 2046-6390)
  • Publisher copyright policies & self-archiving
  • Identifiers: doi: 10.1242/bio.027821, pmc: PMC5703612
  • Subject: Cooperative tumorigenesis | Q | Research Article | Drosophila | Cell fate | Science | Selector genes | Biology (General) | QH301-705.5
    mesheuropmc: genetic structures | animal structures

ABSTRACT During animal development, selector genes determine identities of body segments and those of individual organs. Selector genes are also misexpressed in cancers, although their contributions to tumor progression per se remain poorly understood. Using a model of ... View more
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