High Concentration of Serum Soluble Fas in Patients with Head and Neck Carcinoma: A Comparative Study Before and After Surgical Removal of Tumor

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Seyed Basir Hashemi; Mohammad Javad Fattahi; Mansooreh Jaberipour; Mojtaba Habibagahi; Mahmood Shariati;
(2010)
  • Publisher: Shiraz University of Medical Sciences
  • Journal: Middle East Journal of Cancer (issn: 2008-6709, eissn: 2008-6687)
  • Publisher copyright policies & self-archiving
  • Subject: Fas | Head and neck carcinoma | Soluble Fas | Neoplasms. Tumors. Oncology. Including cancer and carcinogens | RC254-282

Background:Alternative splicing of the Fas transcript can produce a naturalsecreted isoform of this molecule. Some cancer cells can also produce soluble Fas (sFas)which may have suppressive effects on the immune system's anti-tumor response.Elevated concentrations of sF... View more
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