publication . Article . Other literature type . 2013

understanding biocatalyst inhibition by carboxylic acids

Laura R Jarboe; Laura R Jarboe; Liam A. Royce; Ping eLiu;
Open Access
  • Published: 01 Sep 2013 Journal: Frontiers in Microbiology, volume 4 (eissn: 1664-302X, Copyright policy)
  • Publisher: Frontiers Media SA
Abstract
Carboxylic acids are an attractive biorenewable chemical in terms of their flexibility and usage as precursors for a variety of industrial chemicals. It has been demonstrated that such carboxylic acids can be fermentatively produced using engineered microbes, such as Escherichia coli and Saccharomyces cerevisiae. However, like many other attractive biorenewable fuels and chemicals, carboxylic acids become inhibitory to these microbes at concentrations below the desired yield and titer. In fact, their potency as microbial inhibitors is highlighted by the fact that many of these carboxylic acids are routinely used as food preservatives. This review highlights the ...
Subjects
free text keywords: Microbiology (medical), Microbiology, Methionine, chemistry.chemical_compound, chemistry, Intracellular pH, Food Preservatives, Metabolic engineering, Saccharomyces cerevisiae, biology.organism_classification, biology, Biochemistry, Lauric acid, Escherichia coli, medicine.disease_cause, medicine, Respiratory function, tolerance, membrane damage, transporters, acid resistance, biocatalyst robustness, carboxylic acid toxicity, Review Article, QR1-502
Related Organizations
Funded by
NSF| NSF Engineering Reasearch Center for Biorenewable Chemicals (CBiRC)
Project
  • Funder: National Science Foundation (NSF)
  • Project Code: 0813570
  • Funding stream: Directorate for Engineering | Division of Engineering Education & Centers
75 references, page 1 of 5

Abbott D. A.Knijnenburg T. A.de Poorter L. M. I.Reinders M. J. T.Pronk J. T van Maris A. J. A. (2007). Generic and specific transcriptional responses to different weak organic acids in anaerobic chemostat cultures of S. cerevisiae.FEMS Yeast Res. 7 819–833 10.1111/j.1567-1364.2007.00242.x 17484738 [OpenAIRE] [PubMed] [DOI]

Abbott D. A.Zelle R. M.Pronk J. T van Maris A. J. A. (2009). Metabolic engineering of S. cerevisiae for production of carboxylic acids: current status and challenges. FEMS Yeast Res. 9 1123–1136 10.1111/j.1567-1364.2009.00537.x 19566685 [OpenAIRE] [PubMed] [DOI]

Al-Awqati Q. (1999). One hundred years of membrane permeability: does Overton still rule? Nat. Cell Biol. 1 E201–E202 10.1038/70230 10587658 [OpenAIRE] [PubMed] [DOI]

Aono R.Kobayashi H. (1997). Cell surface properties of organic solvent-tolerant mutants of Escherichia coli K-12. Appl. Environ. Microbiol. 63 3637–3642 9293016 [OpenAIRE] [PubMed]

Barua S.Yamashino T.Hasegawa T.Yokoyama K.Torii K.Ohta M. (2002). Involvement of surface polysaccharides in the organic acid resistance of Shiga Toxin-producing Escherichia coli O157:H7. Mol. Microbiol. 43 629–640 10.1046/j.1365-2958.2002.02768.x 11929520 [OpenAIRE] [PubMed] [DOI]

Cabral M. G.Viegas C. A.Sa-Correia I. (2001). Mechanisms underlying the acquisition of resistance to octanoic-acid-induced-death following exposure of S. cerevisiae to mild stress imposed by octanoic acid or ethanol. Arch. Microbiol. 175 301–307 10.1007/s002030100269 11382226 [OpenAIRE] [PubMed] [DOI]

Carlos Serrano-Ruiz J.Pineda A.Mariana Balu A.Luque R.Manuel Campelo J.Angel Romero A. (2012). Catalytic transformations of biomass-derived acids into advanced biofuels. Catal. Today 195 162–168 10.1016/j.cattod.2012.01.009 [OpenAIRE] [DOI]

Carpenter C. E.Broadbent J. R. (2009). External concentration of organic acid anions and pH: key independent variables for studying how organic acids inhibit growth of bacteria in mildly acidic foods. J. Food Sci. 74 R12–R15 10.1111/j.1750-3841.2008.00994.x 19200113 [OpenAIRE] [PubMed] [DOI]

Chang Y. Y.Cronan J. E. (1999). Membrane cyclopropane fatty acid content is a major factor in acid resistance of Escherichia coli. Mol. Microbiol. 33 249–259 10.1046/j.1365-2958.1999.01456.x 10411742 [OpenAIRE] [PubMed] [DOI]

Chotani G.Dodge T.Hsu A.Kumar M.LaDuca R.Trimbur D. (2000). The commercial production of chemicals using pathway engineering. Biochim. Biophys. Acta 1543 434–455 10.1016/S0167-4838(00)00234-X 11150618 [PubMed] [DOI]

Cipak A.Jaganjac M.Tehlivets O.Kohlwein S. D.Zarkovic N. (2008). Adaptation to oxidative stress induced by polyunsaturated fatty acids in yeast. Biochim. Biophys. Acta 1781 283–287 10.1016/j.bbalip.2008.03.010 18452720 [OpenAIRE] [PubMed] [DOI]

Comte K.Holland D. P.Walsby A. E. (2007). Changes in cell turgor pressure related to uptake of solutes by Microcystis sp. strain 8401. FEMS Microbiol. Ecol. 61 399–405 10.1111/j.1574-6941.2007.00356.x 17623025 [OpenAIRE] [PubMed] [DOI]

Cummings J. H.Macfarlane G. T. (1991). The control and consequences of bacterial fermentation in the human colon. J. Appl. Bacteriol. 70 443–459 10.1111/j.1365-2672.1991.tb02739.x 1938669 [OpenAIRE] [PubMed] [DOI]

Desbois A. P.Smith V. J. (2010). Antibacterial free fatty acids: activities, mechanisms of action and biotechnological potential. Appl. Microbiol. Biotechnol. 85 1629–1642 10.1007/s00253-009-2355-3 19956944 [OpenAIRE] [PubMed] [DOI]

DiezGonzalez F.Russell J. B. (1997). The ability of Escherichia coli O157:H7 to decrease its intracellular pH and resist the toxicity of acetic acid. Microbiology 143 1175–1180 10.1099/00221287-143-4-1175 9141680 [OpenAIRE] [PubMed] [DOI]

75 references, page 1 of 5
Powered by OpenAIRE Research Graph
Any information missing or wrong?Report an Issue