publication . Article . 2009

La ciclooxigenasa-2 (COX-2) y el factor de crecimiento epidérmico (EFG) en lesiones epiteliales orales premalignas Cyclooxygenase-2 (COX-2) and epidermal growth factor (EGF) in oral premalignant epithelial lesions

S. Díaz Prado; A. Gallego Guadalupe; J.L. López-Cedrún; J. Ferreras Granado; L. Antón Aparicio;
Open Access English
  • Published: 01 Jun 2009 Journal: Revista Española de Cirugía Oral y Maxilofacial (issn: 1130-0558, Copyright policy)
  • Publisher: Elsevier
Abstract
Las lesiones premalignas orales incluyen eritroplasias (manchas rojas) y leucoplasias (manchas blancas), las cuales se desarrollan a lo largo de superficies epiteliales. Estas lesiones son considerados marcadores en la "carcinogénesis de campo" ya que pacientes con lesiones premalignas orales pueden desarrollar carcinoma de células escamosas (CCS) en el sitio de las lesiones, así como en otros lugares de tracto aerodigestivo superior. Se está haciendo un gran esfuerzo para identificar nuevos biomarcadores SEBs (surrogate endpoint biomarkers) para el carcinoma de células escamosas de cabeza y cuello. Los SEBs candidatos para el carcinoma de células escamosas inva...
Subjects
free text keywords: Factor de crecimiento epidérmico, Ciclooxigenasa-2, Carcinoma de células escamosas de cabeza y cuello, Lesión premaligna oral, Biomarcador, Carcinogénesis de campo, Epidermal growth factor, Cyclooxygenase-2, Head and neck squamous cell carcinoma, Oral premalignant lesion, Biomarker, Field cancerization, Dentistry, RK1-715, Surgery, RD1-811
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