In vitro evaluation of antioxidant and neuroprotective effects of curcumin loaded in Pluronic micelles

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Cvetelina Gorinova ; Denitsa Aluani ; Yordan Yordanov ; Magdalena Kondeva-Burdina ; Virginia Tzankova ; Cvetelina Popova ; Krassimira Yoncheva (2016)
  • Publisher: Taylor & Francis Group
  • Journal: Biotechnology & Biotechnological Equipment (issn: 1310-2818, eissn: 1314-3530)
  • Related identifiers: doi: 10.1080/13102818.2016.1186500
  • Subject: Curcumin | polymeric micelles | antioxidant effect | neuroprotective effect | lipid peroxidation | synaptosomal neurotoxicity | Biotechnology | TP248.13-248.65

Curcumin is a polyphenolic substance with attractive pharmacological activities (e.g. antioxidant, anti-inflammatory, anticancer). Incorporation of curcumin in polymeric micelles could overcome the problems associated with its instability and low aqueous solubility. The... View more
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