publication . Article . 2013

The cariostatic mechanisms of fluoride

Kata Rošin-Grget; Kristina Peroš; Ivana Šutej; Krešimir Bašić;
Open Access
  • Published: 01 Nov 2013 Journal: Acta Medica Academica, volume 42, pages 179-188 (issn: 1840-1848, eissn: 1840-2879, Copyright policy)
  • Publisher: Academy of Sciences and Arts of Bosnia and Herzegovina
Abstract
This article discusses the possible cariostatic mechanisms of the action of fluoride. In the past, fluoride inhibition of caries was ascribed to reduced solubility of enamel due to incorporation of fluoride (F–) into the enamel minerals. The present evidence from clinical and laboratory studies suggests that the caries-preventive mode of action of fluoride is mainly topical. There is convincing evidence that fluoride has a major effect on demineralisation and remineralisation of dental hard tissue. The source of this fluoride could either be fluorapatite (formed due to the incorporation of fluoride into enamel) or calcium fluoride (CaF2)-like precipitates, which...
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Subjects
Medical Subject Headings: stomatognathic diseasesstomatognathic system
free text keywords: General Medicine, Dental caries, Fluorides, Tooth remineralization, Enamel paint, visual_art.visual_art_medium, visual_art, Fluoride, chemistry.chemical_compound, chemistry, Phosphate, Inorganic chemistry, Materials science, Biofilm, Fluorapatite, Fluorine, chemistry.chemical_element, Remineralisation, Saliva, lcsh:Medicine (General), lcsh:R5-920
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