publication . Article . 2016

Betel Leaf Extract (Piper betle L.) Antihyperuricemia Effect Decreases Oxidative Stress by Reducing the Level of MDA and Increase Blood SOD Levels of Hyperuricemia Wistar Rats (Rattus norvegicus)

I Made Sumarya; Nyoman Adiputra; Putra Manuaba; Dewa Sukrama;
Open Access
  • Published: 01 Jun 2016 Journal: Bali Medical Journal, volume 5, page 78 (issn: 2089-1180, eissn: 2302-2914, Copyright policy)
  • Publisher: DiscoverSys, Inc.
Abstract
<p><strong>Background: </strong>Betel leaf extracts (<em>Piper betle</em> L.) antioxidant activity and enzyme inhibitors of XO. Hyperuricemia cause oxidative stress by increasing the formation of reactive oxygen species (ROS) cause lipid peroxidation and oxygenation of low-density lipoprotein cholesterol (LDLc). <strong>Objective:</strong> The aim of this research was to determine the betel leaf extract as an anti hyperuricemia that can lower the blood uric acid levels and oxidative stress by lowering the levels of MDA and increase the SOD of hyperuricemia of the rat’s blood. <strong>Method:</strong><strong> </strong>Experimental research was conducted with the ...
Subjects
Medical Subject Headings: nutritional and metabolic diseases
free text keywords: hyperuricemia, betel leaf extract, oxidative stress, mda and sod., Medicine, R, Medicine (General), R5-920
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