publication . Article . 2011

Acamprosate and Baclofen were Not Effective in the Treatment of Pathological Gambling: Preliminary Blind Rater Comparison Study

Pinhas N. Dannon; Moshe Kotler; Oded Rosenberg; Netta Schoenfeld;
Open Access
  • Published: 01 Jun 2011 Journal: Frontiers in Psychiatry, volume 2 (eissn: 1664-0640, Copyright policy)
  • Publisher: Frontiers Media SA
Abstract
Objectives: Pathological gambling (PG) is a highly prevalent and disabling impulse control disorder. A range of psychopharmacological options are available for the treatment of PG, including selective serotonin reuptake inhibitors, opioid receptor antagonists, anti-addiction drugs, and mood stabilizers. In our preliminary study, we examined the efficacy of two anti-addiction drugs, baclofen and acamprosate, in the treatment of PG. Materials and Methods: Seventeen male gamblers were randomly divided into two groups. Each group received one of the two drugs without being blind to treatment. All patients underwent a comprehensive psychiatric diagnostic evaluation a...
Subjects
free text keywords: Psychiatry and Mental health, Clinical Trial, pathological gambling, GABA, RC435-571, Internal medicine, medicine.medical_specialty, medicine, Psychology, Comparison study, Psychiatry, Impulse control disorder, medicine.disease, Baclofen, chemistry.chemical_compound, chemistry, Acamprosate, medicine.drug, Mood, Behavioral addiction, medicine.symptom, Pathological, Abstinence, media_common.quotation_subject, media_common
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