publication . Article . 2019

Psychological intervention based on psychoneuroimmunology improves clinical evolution, quality of life, and immunity of children with leukemia: A preliminary study:

Josymar Chacin-Fernández; Margarita Chacin Fuenmayor; Lorena Piñerua-Shuhaibar; Heberto Suarez-Roca;
Open Access English
  • Published: 01 Apr 2019 Journal: Health Psychology Open (issn: 2055-1029, Copyright policy)
  • Publisher: SAGE Publishing
Abstract
We conducted a non-randomized, open-label clinical trial to assess whether a psychoneuroimmunology-based intervention enhanced immunity in children with acute lymphoblastic leukemia undergoing chemotherapy. In total, 16 children (44% female) received psychoneuroimmunology-based intervention, whereas 12 (50% female) received health psychoeducation (controls). The primary outcome was immunity markers, being clinical conditions the secondary outcome. Psychoneuroimmunology-based intervention increased immune markers (CD8+ T, B, and natural killer cells, serum immunoglobulin A, and immunoglobulin M) and quality of life, whereas it shortens the duration of fever and u...
Subjects
free text keywords: Psychology, BF1-990, Intervention Study, children, hematology, leukemia, psychological intervention, psychoneuroimmunology, Pediatrics, medicine.medical_specialty, medicine, Clinical trial, Immunity, medicine.disease, Internal medicine, Quality of life, Lymphoblastic Leukemia, business.industry, business
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37 references, page 1 of 3

Andersen BL Farrar WB Golden-Kreutz D et al (2004) Psychological, behavioral, and immune changes after a psychological intervention: a clinical trial. Journal of Clinical Oncology 22(17): 3570–3580.15337807 [OpenAIRE] [PubMed]

Andersen BL Farrar WB Golden-Kreutz D et al (2007) Distress reduction from a psychological intervention contributes to improved health for cancer patients. Brain, Behavior, and Immunity 21(7): 953–961.

Andersen BL Thornton LM Shapiro CL et al (2010) Biobehavioral, immune, and health benefits following recurrence for psychological intervention participants. Clinical Cancer Research 16(12): 3270–3278.20530702 [OpenAIRE] [PubMed]

Antoni MH (2003) Stress management effects on psychological, endocrinological, and immune functioning in men with HIV infection: empirical support for a psychoneuroimmunological model. Stress 6: 173–188.13129811 [PubMed]

Antoni MH (2013) Psychosocial intervention effects on adaptation, disease course and biobehavioral processes in cancer. Brain, Behavior, and Immunity 30: S88–S98.

Barre PV Padmaja G Rana S et al (2018) Stress and quality of life in cancer patients: Medical and psychological intervention. Indian Journal of Psychological Medicine 40(3): 232–238.29875530 [OpenAIRE] [PubMed]

Ben-Shaanan TL Schiller M Azulay-Debby H et al (2018) Modulation of anti-tumor immunity by the brain’s reward system. Nature Communications 9(1): 2723.

Bernabeu VerdúJ (2003) Calidad de vida de Oncologia Pediatrica: Estudio Inicial de un Cuestionario. Valencia: Unitat oncologia pediàtrica Hospital La Fe Avda Available at: http://www.uv.es/jorber2/calidad%20de%20vida%20en%20oncologia%20pediatrica.pdf (accessed 3 October 2017).

Bower JE Kemeny ME Taylor SE et al (2003) Finding positive meaning and its association with natural killer cell cytotoxicity among participants in a bereavement-related disclosure intervention. Annals of Behavioral Medicine 25: 146–155.12704017 [PubMed]

Carlson LE Speca M Patel KD et al (2003) Mindfulness-based stress reduction in relation to quality of life, mood, symptoms of stress, and immune parameters in breast and prostate cancer outpatients. Psychosomatic Medicine 65(4): 571–581.12883107 [OpenAIRE] [PubMed]

Castés M Hagel I Palenque M et al (1999) Immunological changes associated with clinical improvement of asthmatic children subjected to psychosocial intervention. Brain, Behavior, and Immunity 13(1): 1–13.

Castillo-Martínez ID Juárez-Villegas LE Palomo-Colli MA et al (2009) Calidad de vida en niños con leucemia linfoblástica aguda durante la inducción a la remisión mediante el PedsQL Cancer Module©. Boletín Médico del Hospital Infantil de México 66: 410–418.

Chacín de Fernández J (2014 a) Una Batalla Ganada. Mi Lucha Contra La Leucemia. Ediciones Astro Data. Maracaibo: S.A, Maracaibo.

Chacín de Fernández J (2014 b) Una Batalla Ganada. Mi Lucha Contra La Leucemia. Cuaderno De Actividades (Ediciones Astro Data). Maracaibo: S.A, Maracaibo.

Chacín de Fernández J (2014 c) Una Batalla Ganada. Mi Lucha Contra La Leucemia. Audio (Ediciones Astro Data). Maracaibo: S.A, Maracaibo.

37 references, page 1 of 3
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publication . Article . 2019

Psychological intervention based on psychoneuroimmunology improves clinical evolution, quality of life, and immunity of children with leukemia: A preliminary study:

Josymar Chacin-Fernández; Margarita Chacin Fuenmayor; Lorena Piñerua-Shuhaibar; Heberto Suarez-Roca;