publication . Article . Other literature type . 2015

Effect of age on the pathogenesis of duck tembusu virus in Cherry Valley ducks

Li, Ning; Lv, Chuanwei; Yue, Ruichao; Shi, Ying; Wei, Liangmeng; Chai, Tongjie; Liu, Sidang;
Open Access English
  • Published: 08 Jun 2015 Journal: Frontiers in Microbiology, volume 6 (eissn: 1664-302X, Copyright policy)
  • Publisher: Frontiers Media S.A.
Abstract
The effect of host age on the outcome of duck tembusu virus (DTMUV) infection was studied in ducks. Three groups of Cherry Valley ducks at 1, 3, and 7 weeks of age were intramuscularly infected with DTMUV to systematically observe the clinical symptoms, pathological changes, tissue viral loads, and immune responses. Severe clinical symptoms and neurological dysfunction were observed in 1-week-old ducks as early as 2 days post infection (dpi) and some died at 5–7 dpi. Three weeks-old ducks showed similar but milder symptoms and no deaths. However, 7-weeks-old ducks showed only transient loss of appetite. Gross lesions gradually reduced in severity as ducks mature...
Subjects
Medical Subject Headings: virusesanimal diseasesvirus diseasesanimal structures
free text keywords: Microbiology, Original Research, duck tembusu virus, Cherry Valley ducks, age, pathogenesis, immune response, Duck Tembusu virus;, Cherry Valley ducks;, age;, pathogenesis;, QR1-502, Microbiology (medical), Antibody titer, Virus, Viral encephalitis, medicine.disease, medicine, Viral load, Viral pathogenesis, Antibody, biology.protein, biology, Lymph, Virology
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publication . Article . Other literature type . 2015

Effect of age on the pathogenesis of duck tembusu virus in Cherry Valley ducks

Li, Ning; Lv, Chuanwei; Yue, Ruichao; Shi, Ying; Wei, Liangmeng; Chai, Tongjie; Liu, Sidang;