publication . Article . 2008

Thyrotoxicosis-Associated Cholestasis in a Patient with Hepatitis B Cirrhosis

Mohamed Osama Hegazi; Amin Marafie; Mubarak Alajmi;
Open Access English
  • Published: 01 Dec 2008 Journal: Turkish Journal of Endocrinology and Metabolism, volume 12, issue 4, pages 99-100 (issn: 1301-2193, Copyright policy)
  • Publisher: Turkiye Klinikleri
Abstract
Abnormalities in liver function tests were reported in association with hyperthyroidism. Intrahepatic cholestasis is one form of this association. Reversal of hyperbilirubinemia upon correction of hyperthyroidism supports the causal relationship. Most reported cases have occurred in patients without previous liver disease. We report a case of marked cholestatic jaundice associated with hyperthyroidism caused by toxic adenoma in a patient with hepatitis B cirrhosis. Serum bilirubin returned to baseline level after correcting hyperthyroidism with radioiodine therapy. Hyperthyroidism should be considered in the differential diagnosis of cholestasis in association w...
Subjects
Medical Subject Headings: endocrine system diseasesendocrine systemhormones, hormone substitutes, and hormone antagonists
free text keywords: Cholestasis, cirrhosis, hyperthyroidism, hepatitis B, lcsh:Diseases of the endocrine glands. Clinical endocrinology, lcsh:RC648-665
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