publication . Article . Other literature type . 2012

Inhibition of HMGB1 Translocation by Green Tea Extract in Rats Exposed to Environmental Tobacco Smoke

Chaichalotornkul, S.; Suvitayavat, W.; Sangalangkarn, V.; Nawa, Y.; Kikuchi, K.; Kawahara, K.; Saiwichai, T.; Narkpinit, S.; Singhasivanon, P.; Maruyama, I.; ...
Open Access English
  • Published: 01 Jan 2012 Journal: EnvironmentAsia (issn: 1906-1714, Copyright policy)
  • Publisher: Thai Society of Higher Eduction Institutes on Environment
Abstract
Environmental tobacco smoke (ETS) exposure is linked to carcinogenic, oxidative and inflammatory cellular reactions. Green tea polyphenol reportedly plays a role in the prevention of inflammation-related diseases. To evaluate the effects of green tea extract (GTE) on cellular location of High Mobility Group Box-1 (HMGB1) protein, we studied the lung tissue in rats exposed to cigarette smoke (CS). Rats were divided into three groups; CS, CSG, and C, which were groups of CS-treated only, CS-treated with GTE dietary supplement, and the control, respectively. Our findings by immunocytochemistry showed that abundant HMGB1 translocated from the nucleus to the cytoplas...
Subjects
Medical Subject Headings: chemical and pharmacologic phenomena
free text keywords: Green tea, HMGB1, Environmental tobacco smoke (ETS), Nuclear translocation, Geography. Anthropology. Recreation, G, Environmental sciences, GE1-350, Green tea,HMGB1,Environmental tobacco smoke (ETS),Nuclear translocation
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publication . Article . Other literature type . 2012

Inhibition of HMGB1 Translocation by Green Tea Extract in Rats Exposed to Environmental Tobacco Smoke

Chaichalotornkul, S.; Suvitayavat, W.; Sangalangkarn, V.; Nawa, Y.; Kikuchi, K.; Kawahara, K.; Saiwichai, T.; Narkpinit, S.; Singhasivanon, P.; Maruyama, I.; ...