publication . Article . 2016

Averting the foul taste of pediatric medicines improves adherence and can be lifesaving - Pheburane® (sodium phenylbutyrate).

Yona Amitai; Gideon Koren; Michael J. Rieder;
Open Access
  • Published: 01 Oct 2016 Journal: Patient Preference and Adherence, volume Volume 10, pages 2,141-2,144 (eissn: 1177-889X, Copyright policy)
  • Publisher: Dove Medical Press Ltd.
Abstract
Gideon Koren,1 Michael J Rieder,1 Yona Amitai2 1Department of Physiology and Pharmacology, The University of Western Ontario, London, ON, Canada; 2Bar-Ilan University, Ramat Gan, Israel Background: Children’s aversions to poor and mostly bitter tastes and their inability to swallow tablets and capsules are major challenges in pediatric medicine. Sodium phenylbutyrate (NaPB) is a lifesaving waste nitrogen, alternative to urea nitrogen, for individuals suffering from urea cycle disorders. A major issue in the use of NaPB is its highly foul taste, which often leads to children being unable to consume it, resulting in ineffective treatment, or alternatively, n...
Subjects
free text keywords: adherehce, urea cycle disorders, pheburane, Medicine (General), R5-920, Sodium phenylbutyrate, medicine.drug, medicine, Lag time, Gastrostomy, medicine.medical_treatment, Taste, Drug, media_common.quotation_subject, media_common, Intensive care medicine, medicine.medical_specialty, Pediatric Medicine, Urea nitrogen, Bitter tastes, business.industry, business
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