publication . Article . 2017

MicroRNA7 expression in exhaled breath condensate of smokers with chronic obstructive pulmonary disease: A potential biomarker?

Nevine Abd Elfattah; R. Ali-Labib;
Open Access English
  • Published: 01 Oct 2017 Journal: Egyptian Journal of Chest Disease and Tuberculosis (issn: 0422-7638, Copyright policy)
  • Publisher: Wolters Kluwer Medknow Publications
Abstract
Rationale: The global burden of lung cancer is attributed to its poor outcome as it is usually discovered in an advanced stage therefore the constant search for screening protocols among the high risk groups like smokers and chronic obstructive pulmonary disease (COPD). Biomarker testing in exhaled breath condensate (EBC) samples is a simple inexpensive non invasive method. Many previous researches linked the dys-Regulation of microRNAs to the development of lung carcinogenesis. Consequently the aim of this study is to investigate the role microRNA7 as a potential biomarker for early detection of lung cancer among smokers and COPD patients using EBC samples. ...
Subjects
mesheuropmc: respiratory tract diseases
free text keywords: Cigarette smoking, Lung cancer, MicroRNAs, Diseases of the respiratory system, Exhaled breath condensate, RC705-779, Biomarker, Chronic obstructive pulmonary disease
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