Tracking Human Immunodeficiency Virus-1 Infection in the Humanized DRAG Mouse Model

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Jiae Kim ; Jiae Kim ; Kristina K. Peachman ; Kristina K. Peachman ; Ousman Jobe ; Ousman Jobe ; Elaine B. Morrison ; Atef Allam ; Atef Allam ; Linda Jagodzinski ; Sofia A. Casares ; Mangala Rao (2017)
  • Publisher: Frontiers Media S.A.
  • Journal: Frontiers in Immunology (issn: 1664-3224)
  • Related identifiers: doi: 10.3389/fimmu.2017.01405, doi: 10.3389/fimmu.2017.01405/full
  • Subject: human immunodeficiency virus-1 | human immunodeficiency virus vaginal transmission | humanized DRAG mouse | RNA | DNA | quantitative RT-PCR | Immunologic diseases. Allergy | RC581-607

Humanized mice are emerging as an alternative model system to well-established non-human primate (NHP) models for studying human immunodeficiency virus (HIV)-1 biology and pathogenesis. Although both NHP and humanized mice have their own strengths and could never truly ... View more
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