publication . Article . Part of book or chapter of book . 2016

Snake Venom Metalloproteinases

Biological Roles and Participation in the Pathophysiology of Envenomation
Serban Andrei Gaz;
Open Access English
  • Published: 01 Mar 2016 Journal: Acta Medica Marisiensis (issn: 2247-6113, Copyright policy)
  • Publisher: Sciendo
Abstract
<jats:title>Abstract</jats:title><jats:p>As more data are generated from proteome and transcriptome analysis revealing that metalloproteinases represent most of the Viperid and Colubrid venom components authors decided to describe in a short review a classification and some of the multiple activities of snake venom metalloproteinases. SVMPs are classified in three major classes (P-I, P-II and P-III classes) based on the presence of various domain structures and according to their domain organization. Furthermore, P-II and P-III classes were separated in subclasses based on distinctive post-translational modifications. SVMPs are synthesized in a latent form, bein...
Subjects
free text keywords: snake venom metalloproteinases, hemorrhagic activity, hemostatic distruption, ADAM and ADAMTS, SVMPs, Medicine, R
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