Toxicity studies of drugs and chemicals in animals: An overview

Article English OPEN
S. Saganuwan;
  • Publisher: Faculty of Veterinary Medicine, Trakia University, Stara Zagora, Bulgaria
  • Journal: Bulgarian Journal of Veterinary Medicine (issn: 1311-1477, eissn: 1313-3543)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.15547/bjvm.983
  • Subject: median lethal dose | Paracelsus | therapeutic agent | toxicant | Veterinary medicine | SF600-1100

Toxicity study is the investigation of either short or long-term toxic effects of a drug or chemical on animals. The toxicity is dose-dependent as asserted by Paracelsus over 500 years ago. However, short-term toxic effect is determined using median lethal dose (LD50) f... View more
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