publication . Article . 2013

Association of spirochetal infection with Morgellons disease [v1; ref status: indexed, http://f1000r.es/8g]

Marianne J Middelveen; Divya Burugu; Akhila Poruri; Jennie Burke; Peter J Mayne; Eva Sapi; Douglas G Kahn; Raphael B Stricker;
Open Access English
  • Published: 01 Jan 2013 Journal: F1000Research (issn: 2046-1402, Copyright policy)
  • Publisher: F1000 Research Ltd
Abstract
Morgellons disease (MD) is an emerging multisystem illness characterized by skin lesions with unusual filaments embedded in or projecting from epithelial tissue. Filament formation results from abnormal keratin and collagen expression by epithelial-based keratinocytes and fibroblasts. Recent research comparing MD to bovine digital dermatitis, an animal infectious disease with similar skin features, provided clues that spirochetal infection could play an important role in the human disease as it does in the animal illness. Based on histological staining, immunofluorescent staining, electron microscopic imaging and polymerase chain reaction, we report the detectio...
Subjects
free text keywords: Medical Microbiology, Parasitology, Medicine, R, Biology (General), QH301-705.5
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