publication . Article . 2016

Association between Serum Osteopontin Levels and Cardiovascular Risk in Hypothyrodism

Türkan Mete; Gülhan Duman; Eda Melek Ertörer; Emre Bozkırlı; Okan Sefa Bakıner; Neslihan Başçıl Tütüncü;
Open Access English
  • Published: 23 Jun 2016
  • Country: Turkey
Abstract
Purpose: Cardiovascular effects of hypothyroidism are well known. Osteopontin (OPN) is a new inflammatory marker which was first isolated from the bone. Flow-mediated dilatation (FMD), a noninvasive technique to measure this endothelium-dependent function, has been used in several clinical studies to show cardiovascular risks. The aim of our study was to assess FMD value in hypothyroidism patients and to investigate whether plasma OPN level is a parameter which can predict cardiovascular risks in this group of patients. Material and Method: This study included 39 patients who had high levels of thyroid-stimulating hormone (TSH) and 11 healthy euthyroid controls....
Subjects
Medical Subject Headings: stomatognathic systemendocrine system diseasesendocrine systemhormones, hormone substitutes, and hormone antagonists
free text keywords: Hypothyroidism, osteopontin, flow mediated dilatation, atherosclerosis, Diseases of the endocrine glands. Clinical endocrinology, RC648-665, Internal medicine, medicine.medical_specialty, medicine, business.industry, business, Diabetes mellitus, medicine.disease, Endocrinology, biology.protein, biology
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publication . Article . 2016

Association between Serum Osteopontin Levels and Cardiovascular Risk in Hypothyrodism

Türkan Mete; Gülhan Duman; Eda Melek Ertörer; Emre Bozkırlı; Okan Sefa Bakıner; Neslihan Başçıl Tütüncü;