Arctigenin Inhibits Liver Cancer Tumorigenesis by Inhibiting Gankyrin Expression via C/EBPα and PPARα

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Ying Sun; Ying Sun; Yu-jun Tan; Yu-jun Tan; Zhan-zhao Lu; Zhan-zhao Lu; Bing-bing Li; Bing-bing Li; Cheng-hong Sun; Cheng-hong Sun; Tao Li; Tao Li; Li-li Zhao; Li-li Zhao; Zhong Liu; Zhong Liu; Zhong Liu; Gui-min Zhang; Gui-min Zhang; Gui-min Zhang; Jing-chun Yao; Jing-chun Yao; Jing-chun Yao; Jie Li; Jie Li;

(2018)

Publisher: Frontiers Media S.A.

Journal: Frontiers in Pharmacology (issn: 1663-9812)

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Identifiers: doi: 10.3389/fphar.2018.00268/full, doi: 10.3389/fphar.2018.00268
Subject: arctigenin | gankyrin | RM1-950 | Therapeutics. Pharmacology | PPARα | hepatocellular carcinoma | C/EBPα
mesheuropmc: digestive system diseases

Burdock (Arctium lappa) is a popular vegetable in China and Japan that is consumed for its general health benefits. The principal active component of burdock is arctigenin, which shows a range of bioactivities in vivo and in vitro. Here, we investigated the potential an... View more

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