Profiling Prostate Cancer Therapeutic Resistance
Cameron A. Wade
- Publisher: MDPI AG
International Journal of Molecular Sciences,
(issn: 1422-0067, eissn: 1422-0067)
metabolic changes | Chemistry | androgen receptor | Review | QD1-999 | epithelial plasticity | Biology (General) | tumor landscape | QH301-705.5
The major challenge in the treatment of patients with advanced lethal prostate cancer is therapeutic resistance to androgen-deprivation therapy (ADT) and chemotherapy. Overriding this resistance requires understanding of the driving mechanisms of the tumor microenvironm...