Formulation and Evaluation of Extended- Release Tablet of Zolpidem Tartrate by Wet Granulation Technique

Article English OPEN
Fatemeh Pourhashem; Mohammad Reza Avadi;
(2016)
  • Publisher: Islamic Azad University
  • Journal: Journal of Pharmaceutical and Health Sciences (issn: 2228-6780, eissn: 2322-4738)
  • Publisher copyright policies & self-archiving
  • Subject: Zolpidem tartrate | Wet granulation | Hydroxy propyl methyl cellulose (K4M) | Factorial design | ICH guideline | Pharmacy and materia medica | RS1-441 | Public aspects of medicine | RA1-1270

The goal of this study was to design and evaluate extended - release system of the hypnotic agent, Zolpidem tartrate usefulness for the treatment of insomnia. The half-life of this drug is about 1.9 - 3 hours that indicating it a candidate for the extended release... View more
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