Anti-BACE1 and Antimicrobial Activities of Steroidal Compounds Isolated from Marine Urechis unicinctus

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Yong-Zhe Zhu; Jing-Wen Liu; Xue Wang; In-Hong Jeong; Young-Joon Ahn; Chuan-Jie Zhang;
  • Publisher: MDPI AG
  • Journal: Marine Drugs,volume 16,issue 3 (issn: 1660-3397, eissn: 1660-3397)
  • Related identifiers: doi: 10.3390/md16030094, pmc: PMC5867638
  • Subject: Alzheimer’s disease | BACE1 | bioassay-directed isolation | Urechis unicinctus | antimicrobial activity | Article | marine bioactive | Biology (General) | QH301-705.5

The human β-site amyloid cleaving enzyme (BACE1) has been considered as an effective drug target for treatment of Alzheimer’s disease (AD). In this study, Urechis unicinctus (U. unicinctus), which is a Far East specialty food known as innkeeper worm, ethanol extract was... View more
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