publication . Article . 2007

Cost-effectiveness of childhood hepatitis A vaccination in Argentina: a second dose is warranted Efectividad en función del costo de la vacunación infantil contra la hepatitis A en Argentina: se justifica una segunda dosis

Alejandro Ellis; Ricardo W. Rüttimann; R. Jake Jacobs; Allen S. Meyerhoff; Bruce L. Innis;
Open Access English
  • Published: 01 Jun 2007 Journal: Revista Panamericana de Salud Pública (issn: 1020-4989, eissn: 1680-5348, Copyright policy)
  • Publisher: Pan American Health Organization
OBJECTIVES: To investigate the cost-effectiveness of childhood vaccination against hepatitis A in the five geographic regions of Argentina, and to determine whether adding a second dose to the current one-dose schedule would provide health gains justifying its added cost. METHODS: A Markov model was used to consider four immunization options for the 2005 birth cohort: (1) no vaccination; (2) vaccination at 12 months of age, (3) vaccinations at 12 and 72 months of age; or (4) vaccinations at 12 and 18 months of age. Hepatitis A costs and consequences were predicted over 50 years. The cost-effectiveness of first and second vaccine doses was assessed through a rang...
free text keywords: Costos y análisis de costo, hepatitis A, esquema de inmunización, años de vida ajustados por calidad de vida, vacunación, Argentina, Costs and cost analysis, hepatitis A, immunization schedule, quality-adjusted life years, vaccination, Argentina, Medicine, R, Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270
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