EFFECT OF SACUBITRIL/VALSARTAN ON NATRIURESIS, DIURESIS AND BLOOD PRESSURE IN HYPERTENSIVE PATIENTS

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Zh. D. Kobalava ; S. V. Villevalde ; I. A. Meray ; O. I. Lukina (2017)
  • Publisher: Stolichnaya Izdatelskaya Kompaniya
  • Journal: Racionalʹnaâ Farmakoterapiâ v Kardiologii (issn: 1819-6446, eissn: 2225-3653)
  • Related identifiers: doi: 10.20996/1819-6446-2017-13-3-370-377
  • Subject: sacubitril/valsartan | natriuresis | diuresis | blood pressure | cyclic guanosine monophosphate | brain natriuretic peptide | Therapeutics. Pharmacology | RM1-950 | Diseases of the circulatory (Cardiovascular) system | RC666-701

Aim. To study the effect of sacubitril/valsartan compared with valsartan on natriuresis, diuresis, blood pressure (BP) and the level of biomarkers in hypertensive patients.Material and methods. Hypertensive patients (n=16) received sacubitril/valsartan 400 mg QD or vals... View more
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