publication . Article . 2015

Association between Polymorphism of Endothelial Nitric Oxide Synthase Gene (Glu298Asp) and Chronic Heart Failure in Patients with Ischemic Heart Disease and Obesity

O.I. Kadykova; P.P. Kravchun;
Open Access English
  • Published: 06 Apr 2015 Journal: Mìžnarodnij Endokrinologìčnij Žurnal (issn: 2224-0721, eissn: 2307-1427, Copyright policy)
  • Publisher: Publishing House Zaslavsky
Abstract
The article reviewed the links between polymorphism of endothelial nitric oxide synthase gene (Glu298Asp) and the development and progression of chronic heart failure in patients with ischemic heart disease and obesity. There has been a comprehensive survey of 222 patients with ischemic heart disease. Comparison group consisted of 115 patients with ischemic heart disease with normal body weight. The control group included 35 healthy individuals. G allele and genotype G/G polymorphism of the gene of endothelial nitric oxide synthase (Glu298Asp) was associated with the development of ischemic heart disease. The presence of allele G and G/G genotype polymorphism of...
Subjects
free text keywords: ischemic heart disease, obesity, polymorphisms of endothelial nitric oxide synthase gene, chronic heart failure., Diseases of the endocrine glands. Clinical endocrinology, RC648-665, Genotype, Internal medicine, medicine.medical_specialty, medicine, Diabetes mellitus, medicine.disease, Polymorphism (computer science), Concomitant, Heart failure, Allele, business.industry, business, Endocrinology, Disease
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