publication . Article . 2018

In vitro antimalarial activity of Calophyllum bicolor and hemozoin crystals observed by Transmission Electron Microscope (TEM)

Jamilah Abbas;
Open Access English
  • Published: 01 Jan 2018 Journal: MATEC Web of Conferences (issn: 2261-236X, Copyright policy)
  • Publisher: EDP Sciences
Abstract
<jats:p><jats:italic>Objective</jats:italic> : In continuation of our antimalarial candidate drug discovery program on Indonesia medicinal plants especially from stem bark of <jats:italic>Calophyllum bicolor. Metode</jats:italic> : We extracted of bioactive crude extract with hexane, acetone and methanol from stem bark of Calophyllum bicolor and evaluated their antimalarial activity by using parasite <jats:italic>Plasmodium falciparum in vitro. Results:</jats:italic> Methanol fraction showed most active and potent antimalarial activity dose dependent in <jats:italic>in vitro</jats:italic> experiments with IC<jats:sub>50</jats:sub> = 0.52 ppb, and hexane fraction...
Subjects
free text keywords: Calophyllum bicolor, Plasmodium falciparum, in-vitro, TEM (Transmition Electron Mecroscope), Engineering (General). Civil engineering (General), TA1-2040, Acetone, chemistry.chemical_compound, chemistry, Nuclear chemistry, Methanol, In vitro, biology.organism_classification, biology, Hexane, Medicinal plants, Hemozoin

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publication . Article . 2018

In vitro antimalarial activity of Calophyllum bicolor and hemozoin crystals observed by Transmission Electron Microscope (TEM)

Jamilah Abbas;