publication . Article . Other literature type . 2018

Kinases and Cancer.

Pascale Gaudet; Egle Zalyte; Amos Marc Bairoch; Jonas Cicenas;
Open Access
  • Published: 01 Mar 2018 Journal: Cancers, volume 10, page 63 (eissn: 2072-6694, Copyright policy)
  • Publisher: MDPI AG
Abstract
Protein kinases are a large family of enzymes catalyzing protein phosphorylation. The human genome contains 518 protein kinase genes, 478 of which belong to the classical protein kinase family and 40 are atypical protein kinases [...].
Subjects
free text keywords: Cancer Research, Oncology, Editorial, n/a, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, cell lung-cancer ; growth-factor receptor ; in-situ hybridization ; breast-cancer ; poor-prognosis ; gene amplification ; colorectal-cancer ; epigenetic inactivation ; pancreatic-cancer ; targeted therapy, Biology, Protein phosphorylation, Enzyme, chemistry.chemical_classification, chemistry, Cancer, medicine.disease, medicine, Human genome, Gene, Protein kinase A, Kinase, Biochemistry, ddc:616
64 references, page 1 of 5

Hunter, T., Cooper, J.A.. Protein-tyrosine kinases. Annu. Rev. Biochem.. 1985; 54: 897-930 [PubMed] [DOI]

Gaudet, P., Michel, P.A., Zahn-Zabal, M., Britan, A., Cusin, I., Domagalski, M., Duek, P.D., Gateau, A., Gleizes, A., Hinard, V.. The nextprot knowledgebase on human proteins: 2017 update. Nucleic Acids Res.. 2017; 45: D177-D182 [OpenAIRE] [PubMed] [DOI]

Nukaga, S., Yasuda, H., Tsuchihara, K., Hamamoto, J., Masuzawa, K., Kawada, I., Naoki, K., Matsumoto, S., Mimaki, S., Ikemura, S.. Amplification of egfr wild-type alleles in non-small cell lung cancer cells confers acquired resistance to mutation-selective egfr tyrosine kinase inhibitors. Cancer Res.. 2017; 77: 2078-2089 [PubMed] [DOI]

Khan, S.A., Zeng, Z., Shia, J., Paty, P.B.. Egfr gene amplification and kras mutation predict response to combination targeted therapy in metastatic colorectal cancer. Pathol. Oncol. Res.. 2017; 23: 673-677 [OpenAIRE] [PubMed] [DOI]

Chang, N., Lee, H.W., Lim, J.E., Jeong, D.E., Song, H.J., Kim, S., Nam, D.H., Sung, H.H., Jeong, B.C., Seo, S.I.. Establishment and antitumor effects of dasatinib and pki-587 in bd-138t, a patient-derived muscle invasive bladder cancer preclinical platform with concomitant egfr amplification and pten deletion. Oncotarget. 2016; 7: 51626-51639 [OpenAIRE] [PubMed] [DOI]

Zhou, C., Zhu, L., Ji, J., Ding, F., Wang, C., Cai, Q., Yu, Y., Zhu, Z., Zhang, J.. Egfr high expression, but not kras status, predicts sensitivity of pancreatic cancer cells to nimotuzumab treatment in vivo. Curr. Cancer Drug Targets. 2017; 17: 89-97 [OpenAIRE] [PubMed] [DOI]

Cho, E.Y., Choi, Y.L., Han, J.J., Kim, K.M., Oh, Y.L.. Expression and amplification of her2, egfr and cyclin d1 in breast cancer: Immunohistochemistry and chromogenic in situ hybridization. Pathol. Int.. 2008; 58: 17-25 [OpenAIRE] [PubMed] [DOI]

Morey, A.L., Brown, B., Farshid, G., Fox, S.B., Francis, G.D., McCue, G., von Neumann-Cosel, V., Bilous, M.. Determining her2 (erbb2) amplification status in women with breast cancer: Final results from the australian in situ hybridisation program. Pathology. 2016; 48: 535-542 [OpenAIRE] [PubMed] [DOI]

Hoffmann, M., Pasch, S., Schamberger, T., Maneck, M., Mohlendick, B., Schumacher, S., Brockhoff, G., Knoefel, W.T., Izbicki, J., Polzer, B.. Diagnostic pathology of early systemic cancer: Erbb2 gene amplification in single disseminated cancer cells determines patient survival in operable esophageal cancer. Int. J. Cancer. 2017; 142: 833-843 [OpenAIRE] [PubMed] [DOI]

Wang, Y.K., Yang, B.F., Yun, T., Zhu, C.Y., Li, C.Y., Jiang, B., Wang, G.P., Wang, S.N., Li, Y.Y., Zhu, M.L.. Methods and significance of the combined detection of her2 gene amplification and chemosensitivity in gastric cancer. Cancer Biomark.. 2017; 21: 439-447 [PubMed] [DOI]

Han, C.P., Hsu, J.D., Yao, C.C., Lee, M.Y., Ruan, A., Tyan, Y.S., Yang, S.F., Chiang, H.. Her2 gene amplification in primary mucinous ovarian cancer: A potential therapeutic target. Histopathology. 2010; 57: 763-764 [OpenAIRE] [PubMed] [DOI]

Xu, C.W., Wang, W.X., Wu, M.J., Zhu, Y.C., Zhuang, W., Lin, G., Du, K.Q., Huang, Y.J., Chen, Y.P., Chen, G.. Comparison of the c-met gene amplification between primary tumor and metastatic lymph nodes in non-small cell lung cancer. Thorac. Cancer. 2017; 8: 417-422 [OpenAIRE] [PubMed] [DOI]

An, X., Wang, F., Shao, Q., Wang, F.H., Wang, Z.Q., Wang, Z.Q., Chen, C., Li, C., Luo, H.Y., Zhang, D.S.. Met amplification is not rare and predicts unfavorable clinical outcomes in patients with recurrent/metastatic gastric cancer after chemotherapy. Cancer. 2014; 120: 675-682 [OpenAIRE] [PubMed] [DOI]

Di Renzo, M.F., Olivero, M., Giacomini, A., Porte, H., Chastre, E., Mirossay, L., Nordlinger, B., Bretti, S., Bottardi, S., Giordano, S.. Overexpression and amplification of the met/hgf receptor gene during the progression of colorectal cancer. Clin. Cancer Res.. 1995; 1: 147-154 [OpenAIRE] [PubMed]

Miwa, W., Yasuda, J., Murakami, Y., Yashima, K., Sugano, K., Sekine, T., Kono, A., Egawa, S., Yamaguchi, K., Hayashizaki, Y.. Isolation of DNA sequences amplified at chromosome 19q13.1-q13.2 including the akt2 locus in human pancreatic cancer. Biochem. Biophys. Res. Commun.. 1996; 225: 968-974 [OpenAIRE] [PubMed] [DOI]

64 references, page 1 of 5
Abstract
Protein kinases are a large family of enzymes catalyzing protein phosphorylation. The human genome contains 518 protein kinase genes, 478 of which belong to the classical protein kinase family and 40 are atypical protein kinases [...].
Subjects
free text keywords: Cancer Research, Oncology, Editorial, n/a, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, cell lung-cancer ; growth-factor receptor ; in-situ hybridization ; breast-cancer ; poor-prognosis ; gene amplification ; colorectal-cancer ; epigenetic inactivation ; pancreatic-cancer ; targeted therapy, Biology, Protein phosphorylation, Enzyme, chemistry.chemical_classification, chemistry, Cancer, medicine.disease, medicine, Human genome, Gene, Protein kinase A, Kinase, Biochemistry, ddc:616
64 references, page 1 of 5

Hunter, T., Cooper, J.A.. Protein-tyrosine kinases. Annu. Rev. Biochem.. 1985; 54: 897-930 [PubMed] [DOI]

Gaudet, P., Michel, P.A., Zahn-Zabal, M., Britan, A., Cusin, I., Domagalski, M., Duek, P.D., Gateau, A., Gleizes, A., Hinard, V.. The nextprot knowledgebase on human proteins: 2017 update. Nucleic Acids Res.. 2017; 45: D177-D182 [OpenAIRE] [PubMed] [DOI]

Nukaga, S., Yasuda, H., Tsuchihara, K., Hamamoto, J., Masuzawa, K., Kawada, I., Naoki, K., Matsumoto, S., Mimaki, S., Ikemura, S.. Amplification of egfr wild-type alleles in non-small cell lung cancer cells confers acquired resistance to mutation-selective egfr tyrosine kinase inhibitors. Cancer Res.. 2017; 77: 2078-2089 [PubMed] [DOI]

Khan, S.A., Zeng, Z., Shia, J., Paty, P.B.. Egfr gene amplification and kras mutation predict response to combination targeted therapy in metastatic colorectal cancer. Pathol. Oncol. Res.. 2017; 23: 673-677 [OpenAIRE] [PubMed] [DOI]

Chang, N., Lee, H.W., Lim, J.E., Jeong, D.E., Song, H.J., Kim, S., Nam, D.H., Sung, H.H., Jeong, B.C., Seo, S.I.. Establishment and antitumor effects of dasatinib and pki-587 in bd-138t, a patient-derived muscle invasive bladder cancer preclinical platform with concomitant egfr amplification and pten deletion. Oncotarget. 2016; 7: 51626-51639 [OpenAIRE] [PubMed] [DOI]

Zhou, C., Zhu, L., Ji, J., Ding, F., Wang, C., Cai, Q., Yu, Y., Zhu, Z., Zhang, J.. Egfr high expression, but not kras status, predicts sensitivity of pancreatic cancer cells to nimotuzumab treatment in vivo. Curr. Cancer Drug Targets. 2017; 17: 89-97 [OpenAIRE] [PubMed] [DOI]

Cho, E.Y., Choi, Y.L., Han, J.J., Kim, K.M., Oh, Y.L.. Expression and amplification of her2, egfr and cyclin d1 in breast cancer: Immunohistochemistry and chromogenic in situ hybridization. Pathol. Int.. 2008; 58: 17-25 [OpenAIRE] [PubMed] [DOI]

Morey, A.L., Brown, B., Farshid, G., Fox, S.B., Francis, G.D., McCue, G., von Neumann-Cosel, V., Bilous, M.. Determining her2 (erbb2) amplification status in women with breast cancer: Final results from the australian in situ hybridisation program. Pathology. 2016; 48: 535-542 [OpenAIRE] [PubMed] [DOI]

Hoffmann, M., Pasch, S., Schamberger, T., Maneck, M., Mohlendick, B., Schumacher, S., Brockhoff, G., Knoefel, W.T., Izbicki, J., Polzer, B.. Diagnostic pathology of early systemic cancer: Erbb2 gene amplification in single disseminated cancer cells determines patient survival in operable esophageal cancer. Int. J. Cancer. 2017; 142: 833-843 [OpenAIRE] [PubMed] [DOI]

Wang, Y.K., Yang, B.F., Yun, T., Zhu, C.Y., Li, C.Y., Jiang, B., Wang, G.P., Wang, S.N., Li, Y.Y., Zhu, M.L.. Methods and significance of the combined detection of her2 gene amplification and chemosensitivity in gastric cancer. Cancer Biomark.. 2017; 21: 439-447 [PubMed] [DOI]

Han, C.P., Hsu, J.D., Yao, C.C., Lee, M.Y., Ruan, A., Tyan, Y.S., Yang, S.F., Chiang, H.. Her2 gene amplification in primary mucinous ovarian cancer: A potential therapeutic target. Histopathology. 2010; 57: 763-764 [OpenAIRE] [PubMed] [DOI]

Xu, C.W., Wang, W.X., Wu, M.J., Zhu, Y.C., Zhuang, W., Lin, G., Du, K.Q., Huang, Y.J., Chen, Y.P., Chen, G.. Comparison of the c-met gene amplification between primary tumor and metastatic lymph nodes in non-small cell lung cancer. Thorac. Cancer. 2017; 8: 417-422 [OpenAIRE] [PubMed] [DOI]

An, X., Wang, F., Shao, Q., Wang, F.H., Wang, Z.Q., Wang, Z.Q., Chen, C., Li, C., Luo, H.Y., Zhang, D.S.. Met amplification is not rare and predicts unfavorable clinical outcomes in patients with recurrent/metastatic gastric cancer after chemotherapy. Cancer. 2014; 120: 675-682 [OpenAIRE] [PubMed] [DOI]

Di Renzo, M.F., Olivero, M., Giacomini, A., Porte, H., Chastre, E., Mirossay, L., Nordlinger, B., Bretti, S., Bottardi, S., Giordano, S.. Overexpression and amplification of the met/hgf receptor gene during the progression of colorectal cancer. Clin. Cancer Res.. 1995; 1: 147-154 [OpenAIRE] [PubMed]

Miwa, W., Yasuda, J., Murakami, Y., Yashima, K., Sugano, K., Sekine, T., Kono, A., Egawa, S., Yamaguchi, K., Hayashizaki, Y.. Isolation of DNA sequences amplified at chromosome 19q13.1-q13.2 including the akt2 locus in human pancreatic cancer. Biochem. Biophys. Res. Commun.. 1996; 225: 968-974 [OpenAIRE] [PubMed] [DOI]

64 references, page 1 of 5
Any information missing or wrong?Report an Issue