Chikungunya Virus Strains Show Lineage-Specific Variations in Virulence and Cross-Protective Ability in Murine and Nonhuman Primate Models

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Rose M. Langsjoen; Sherry L. Haller; Chad J. Roy; Heather Vinet-Oliphant; Nicholas A. Bergren; Jesse H. Erasmus; Jill A. Livengood; Tim D. Powell; Scott C. Weaver; Shannan L. Rossi; Mark R. Denison;

Chikungunya virus (CHIKV) is a reemerging arbovirus capable of causing explosive outbreaks of febrile illness, polyarthritis, and polyarthralgia, inflicting severe morbidity on affected populations. CHIKV can be genetically classified into 3 major lineages: West African... View more
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