publication . Article . 2007

Lesión celular del miocardio y actividad de la ATPsintasa mitocondrial en ratas infectadas con una cepa colombiana de Trypanosoma cruzi

Dairo Alonso Rendón; Carlos M. Genes; Omar Triana;
Open Access
  • Published: 01 Sep 2007 Journal: Biomédica, volume 27, page 40 (issn: 0120-4157, Copyright policy)
  • Publisher: Instituto Nacional de Salud (Colombia)
Abstract
Introducción. La enfermedad de Chagas es la principal causa de cardiomiopatía crónica en regiones endémicas de Latinoamérica. Alteraciones en el metabolismo energético mitocondrial cardiaco causadas por Trypanosoma cruzi pueden estar involucradas en el desarrollo de esta cardiomiopatía. Objetivo. En este trabajo se investigó la lesión celular del miocardio de ratas durante una infección por la cepa colombiana Mg8 de Trypanosoma cruzi y la actividad de la ATPsintasa mitocondrial para correlacionar el daño al miocardio con el metabolismo energético mitocondrial. Materiales y métodos. Se utilizaron grupos de cinco ratas, las cuales fueron infectadas con tripomastig...
Subjects
free text keywords: enfermedad de Chagas, miocardiopatía chagásica, metabolismo energético, mitocondria, Chagas cardiomyopathy, energy metabolism, mitochondria, General Biochemistry, Genetics and Molecular Biology, General Medicine, Lesion, medicine.symptom, medicine, Cardiomyopathy, medicine.disease, Trypanosoma cruzi, biology.organism_classification, biology, Parasite hosting, Mitochondrion, Strain (chemistry), Pathology, medicine.medical_specialty, Chagas disease, Tropism, energy metabolism, mitochondria, R, Arctic medicine. Tropical medicine, RC955-962
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publication . Article . 2007

Lesión celular del miocardio y actividad de la ATPsintasa mitocondrial en ratas infectadas con una cepa colombiana de Trypanosoma cruzi

Dairo Alonso Rendón; Carlos M. Genes; Omar Triana;