Elimination of IL-13 Reverses Established Goblet Cell Metaplasia into Ciliated Epithelia in Airway Epithelial Cell Culture

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Mitsuko Kondo; Jun Tamaoki; Kiyoshi Takeyama; Kazuo Isono; Kiyomi Kawatani; Takehiro Izumo; Atsushi Nagai;

Background: Interleukin (IL)-13 induces goblet cell metaplasia and plays an important role in mucus hypersecretion in asthma. We previously reported that IL-13 induced goblet cell differentiation along with less ciliated cell differentiation in guinea pig tracheal epith... View more
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