Elimination of IL-13 Reverses Established Goblet Cell Metaplasia into Ciliated Epithelia in Airway Epithelial Cell Culture

Article English OPEN
Mitsuko Kondo; Jun Tamaoki; Kiyoshi Takeyama; Kazuo Isono; Kiyomi Kawatani; Takehiro Izumo; Atsushi Nagai;
(2006)

Background: Interleukin (IL)-13 induces goblet cell metaplasia and plays an important role in mucus hypersecretion in asthma. We previously reported that IL-13 induced goblet cell differentiation along with less ciliated cell differentiation in guinea pig tracheal epith... View more
Share - Bookmark