publication . Other literature type . Article . 2018

Antioxidant and Anti-Osteoporosis Activities of Chemical Constituents of the Stems of Zanthoxylum piperitum

Seo Young Yang; Sang-Hyun Lee; Bui Huu Tai; Hae Dong Jang; Young Ho Kim;
Open Access
  • Published: 01 Feb 2018
  • Publisher: MDPI AG
Two new lignans, zanthoxyloside C (1) and zanthoxyloside D (2), together with nine known compounds comprising lignans (3–5), flavonoids (6–8), and phenolics (9–11), were isolated from the methanol extract of the stems of Zanthoxylum piperitum. All isolates were evaluated for their antioxidant and anti-osteoporotic activities using oxygen radical absorbance capacity (ORAC), cupric reducing antioxidant capacity (CUPRAC), and tartrate-resistant acid phosphatase (TRAP) assays. Compounds 7–10 showed peroxyl radical-scavenging capacities and 4, 6–7, and 9 showed reducing capacities. Moreover, compounds 3, 6–9, and 11 significantly suppressed TRAP activities. These res...
Persistent Identifiers
free text keywords: Zanthoxylum piperitum, Antioxidant, Anti-osteoporosis, ORAC, CUPRAC, TRAP, Organic Chemistry, Article, lcsh:Organic chemistry, lcsh:QD241-441, Chemistry, Oxygen radical absorbance capacity, biology.organism_classification, biology, Methanol, chemistry.chemical_compound, Anti osteoporosis, medicine.medical_treatment, medicine, Chemical constituents, Acid phosphatase, biology.protein, Food science, Antioxidant capacity
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