publication . Article . 2015

Simultaneous diagnosis and drug delivery by silymarin-loaded magnetic nanoparticles

Farhad Khoeini;
Open Access English
  • Published: 01 Jul 2015 Journal: Nanomedicine Journal (issn: 2322-3049, eissn: 2322-5904, Copyright policy)
  • Publisher: Mashhad University of Medical Sciences
Abstract
Objective(s): The aim of this work was to prepare and characterize magnetic nanoparticles (MNPs) as theranostic system to act simultaneously as drug carrier and MRI contrast agent. Chitosan-coated MNPs (CMNPs) were prepared and loaded with silymarin. Silymarin-loaded CMNPs were characterized with various techniques and their potential as MRI contrast agent was also evaluated. Materials and Methods:The chitosan-coated MNPs were prepared by coprecipitation method and were loaded with silymarin. The synthesized nanoparticles were characterized by various techniques including SEM, TEM, X‐ray diffraction (XRD), FTIR and vibrating sample magnetometer (VSM). In vitro d...
Subjects
free text keywords: Chitosan, Drug delivery systems, Magnetite, MRI contrast agent, Silymarin, Medicine (General), R5-920
Related Organizations
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publication . Article . 2015

Simultaneous diagnosis and drug delivery by silymarin-loaded magnetic nanoparticles

Farhad Khoeini;