publication . Article . 2014

Temperature of cutaneous and subcutaneous tissue during the application of aerosols in rats

Rodrigo Plentz;
Open Access English
  • Published: 07 Oct 2014 Journal: Acta Scientiarum: Health Sciences (issn: 1679-9291, eissn: 1807-8648, Copyright policy)
  • Publisher: Universidade Estadual de Maringá
Abstract
This study compared the thermal changes of cutaneous and subcutaneous tissues exposed to different aerosols. Thirty-six adults Wistar rats were arranged in two treatment groups, one exposed to methyl salicylate (GSM; n = 9 skin and n = 9 subcutaneous) and the other exposed to diclofenac diethylammonium (GDD; n = 9 skin and n = 9 subcutaneous) aerosols. Five jets were applied for one-second through an apparatus to reduce spray dispersion (3 cmdiameter) in the lateral left thigh of the animals. Temperatures were measured every minute (min.) during 30 min., with a digital thermometer. In the skin tissue the sensor was positioned manually, in the subcutaneous tissue...
Subjects
free text keywords: aerosols, inflammation, physical therapy, induced hypothermia, cryotherapy, Medicine (General), R5-920, Pharmacy and materia medica, RS1-441
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