publication . Article . Preprint . Other literature type . 2017

A Review on Recent Advances in Stabilizing Peptides/Proteins upon Fabrication in Hydrogels from Biodegradable Polymers

Faisal Raza; Hajra Zafar; Ying Zhu; Yuan Ren; Aftab -Ullah; Asif Khan; Xinyi He; Han Han; Md Aquib; Kofi Boakye-Yiadom; ...
Open Access English
  • Published: 30 Oct 2017 Journal: Pharmaceutics (issn: 1999-4923, Copyright policy)
  • Publisher: MDPI AG
Hydrogels evolved as an outstanding carrier material for local and controlled drug delivery that tend to overcome the shortcomings of old conventional dosage forms for small drugs (NSAIDS) and large peptides and proteins. The aqueous swellable and crosslinked polymeric network structure of hydrogels is composed of various natural, synthetic and semisynthetic biodegradable polymers. Hydrogels have remarkable properties of functionality, reversibility, sterilizability, and biocompatibility. All these dynamic properties of hydrogels have increased the interest in their use as a carrier for peptides and proteins to be released slowly in a sustained manner. Peptide a...
Medical Subject Headings: technology, industry, and agriculturemacromolecular substancescomplex mixtures
free text keywords: nanotechnology, hydrogels, peptides, proteins, crosslinked networks, controlled release, biodegradable polymers, Pharmacy and materia medica, RS1-441, Review, Pharmaceutical Science, Biodegradable polymer, Biocompatibility, Medicine, business.industry, business, Drug delivery, Self-healing hydrogels, Small molecule, Biochemistry, Polymer, chemistry.chemical_classification, chemistry, Peptide
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