publication . Article . 2017

Drug–drug interaction of microdose and regular-dose omeprazole with a CYP2C19 inhibitor and inducer

Park G; Bae SH; Park W; Han S; Park M; Shin S; Shin YG; Yim DS;
Open Access English
  • Published: 01 Mar 2017 Journal: Drug Design (issn: 1177-8881, Copyright policy)
  • Publisher: Dove Medical Press
Abstract
Gab-jin Park,1 Soo Hyeon Bae,1 Wan-Su Park,1 Seunghoon Han,1 Min-Ho Park,2 Seok-Ho Shin,2 Young G Shin,2 Dong-Seok Yim1,2 1Department of Clinical Pharmacology and Therapeutics, Seoul St Mary’s Hospital, PIPET (Pharmacometrics Institute for Practical Education and Training), College of Medicine, Catholic University of Korea, Seoul, South Korea; 2College of Pharmacy, Chungnam National University, Daejeon, South Korea Purpose: A microdose drug–drug interaction (DDI) study may be a valuable tool for anticipating drug interaction at therapeutic doses. This study aimed to compare the magnitude of DDIs at microdoses and regular doses to explore the applicab...
Subjects
free text keywords: drug–drug interaction, microdose, CYP2C19, Therapeutics. Pharmacology, RM1-950
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