publication . Article . 2017

Drug–drug interaction of microdose and regular-dose omeprazole with a CYP2C19 inhibitor and inducer

Park G; Bae SH; Park W; Han S; Park M; Shin S; Shin YG; Yim DS;
Open Access English
  • Published: 01 Mar 2017 Journal: Drug Design (issn: 1177-8881, Copyright policy)
  • Publisher: Dove Medical Press
Abstract
Gab-jin Park,1 Soo Hyeon Bae,1 Wan-Su Park,1 Seunghoon Han,1 Min-Ho Park,2 Seok-Ho Shin,2 Young G Shin,2 Dong-Seok Yim1,2 1Department of Clinical Pharmacology and Therapeutics, Seoul St Mary’s Hospital, PIPET (Pharmacometrics Institute for Practical Education and Training), College of Medicine, Catholic University of Korea, Seoul, South Korea; 2College of Pharmacy, Chungnam National University, Daejeon, South Korea Purpose: A microdose drug–drug interaction (DDI) study may be a valuable tool for anticipating drug interaction at therapeutic doses. This study aimed to compare the magnitude of DDIs at microdoses and regular doses to explore the applicab...
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Subjects
free text keywords: drug–drug interaction, microdose, CYP2C19, Therapeutics. Pharmacology, RM1-950
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Drug Design, Development and Therapy
Article . 2017
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