publication . Article . 2017

Symptomatic Congenital Cytomegalovirus Infection in Children of Seropositive Women

Ines Mack; Marie-Anne Burckhardt; Marie-Anne Burckhardt; Ulrich Heininger; Friederike Prüfer; Sven Schulzke; Sven Wellmann;
Open Access English
  • Published: 09 Jun 2017 Journal: Frontiers in Pediatrics (issn: 2296-2360, Copyright policy)
  • Publisher: Frontiers Media S.A.
Abstract
Cytomegalovirus (CMV) is the most frequent congenital virus infection worldwide. The risk of congenital CMV (cCMV) transmission is highest in seronegative women who acquire primary CMV infection during pregnancy. A growing body of evidence indicates that secondary CMV infections in pregnant women with preconceptual immunity (either through reactivation of latent virus or re-infection with a new strain of CMV) contribute to a much greater proportion of symptomatic cCMV than was previously thought. Here, we describe a case of symptomatic cCMV infection in the newborn of a woman with proven immunity prior to pregnancy. Diagnosis was confirmed by CMV PCR from amniot...
Subjects
free text keywords: cytomegalovirus infections, pregnancy, hearing loss, calcification, blueberry muffin, magnetic resonance imaging, Pediatrics, RJ1-570, Case Report, neuroimaging, Jaundice, medicine.symptom, medicine, medicine.disease, Sensorineural hearing loss, business.industry, business, Hepatosplenomegaly, medicine.medical_specialty, Ganciclovir, medicine.drug, Immunology, Seroconversion, Intensive care medicine, Valganciclovir
Communities
Neuroinformatics
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publication . Article . 2017

Symptomatic Congenital Cytomegalovirus Infection in Children of Seropositive Women

Ines Mack; Marie-Anne Burckhardt; Marie-Anne Burckhardt; Ulrich Heininger; Friederike Prüfer; Sven Schulzke; Sven Wellmann;