publication . Article . 2017

Anticancer potency of black sea cucumber (Holothuria atra) from Mentawai Islands, Indonesia

Mieke Hemiawati Satari; Utmi Arma; Syafruddin Ilyas; Dian Handayani;
Open Access English
  • Published: 01 Mar 2017 Journal: Padjadjaran Journal of Dentistry (issn: 1979-0201, eissn: 2549-6212, Copyright policy)
  • Publisher: Universitas Padjadjaran
Abstract
<jats:p>Introduction: The source of bioactive compounds believed to have strong anticancer potency is derived from sea cucumber. Black sea cucumber (Holothuria atra) is a dominant species in Mentawai Islands, West Sumatera, Indonesia. Key factor compound that acts as anticancer in sea cucumber extract is tritepenoid also known as Frondoside A. The purpose of this study was to determine the effectiveness of the active compound taken from black sea cucumber as anticancer. Methods: Methods used was experimental laboratory. Anticancer activity of black sea cucumber was determined by using the MTT assay cytotoxic test to measure the IC50. Cytotoxic test was conducted...
Subjects
free text keywords: Black sea cucumber (Holothuria atra), Anticancer, Supri's Clone 1 (SP-CI), Dentistry, RK1-715, MTT assay, Sea cucumber, biology.organism_classification, biology, Black sea, IC50, Active compound, Holothuria atra, Potency, Botany, Sea cucumber extract
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