publication . Article . 2015

MICRONEEDLE STRUCTURE DESIGN AND OPTIMIZATION USING GENETIC ALGORITHM

Ismail, N. A.; SIEW CHIN NEOH; Sabani, N.; Taib, B. N.;
Open Access English
  • Published: 01 Jul 2015 Journal: Journal of Engineering Science and Technology (issn: 1823-4690, Copyright policy)
  • Publisher: Taylor's University
Abstract
This paper presents a Genetic Algorithm (GA) based microneedle design and analysis. GA is an evolutionary optimization technique that mimics the natural biological evolution. The design of microneedle structure considers the shape of microneedle, material used, size of the array, the base of microneedle, the lumen base, the height of microneedle, the height of the lumen, and the height of the drug container or reservoir. The GA is executed in conjunction with ANSYS simulation system to assess the design specifications. The GA uses three operators which are reproduction, crossover and mutation to manipulate the genetic composition of the population. In this resea...
Subjects
free text keywords: Microneedle, MEMS, Optimization, Genetic Algorithm, Design and specifications, Engineering (General). Civil engineering (General), TA1-2040, Technology (General), T1-995
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publication . Article . 2015

MICRONEEDLE STRUCTURE DESIGN AND OPTIMIZATION USING GENETIC ALGORITHM

Ismail, N. A.; SIEW CHIN NEOH; Sabani, N.; Taib, B. N.;