Bile acid supplementation decreases body mass gain in C57BL/6J but not 129S6/SvEvTac mice without increasing energy expenditure

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Tobias Fromme; Kristina Hüttinger; Stefanie Maurer; Yongguo Li; Thomas Gantert; Jarlei Fiamoncini; Hannelore Daniel; Sören Westphal; Martin Klingenspor;
  • Publisher: Nature Publishing Group
  • Journal: Scientific Reports (issn: 2045-2322)
  • Related identifiers: doi: 10.1038/s41598-018-37464-z
  • Subject: Medicine | R | Science | Q

Abstract Supplementation of cholate to a high fat diet can protect mice from diet-induced, increased body mass gain. It has been hypothesized that uncoupling protein 1 dependent, non-shivering thermogenesis in brown adipocytes provides the mechanism of increased energy ... View more
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