publication . Article . 2009

Magnetic immobilization and electrochemical detection of leukemia K562 cells

Xueen Jia; Liang Tan; Yaping Zhou; Xiangfu Jiang; Qingji Xie; Hao Tang; Shouzhuo Yao;
Open Access English
  • Published: 01 Jan 2009 Journal: Electrochemistry Communications (issn: 1388-2481, Copyright policy)
  • Publisher: Elsevier
A new protocol was proposed for rapid magnetic isolation, immobilization and electrochemical detection of leukemia K562 cells via their decoration with cationic magnetic nanoparticles (CMNPs). The CMNPs (3-aminopropyltriethoxysilane-treated Fe3O4) were synthesized in liquid solution and characterized by transmission electron microscopy. After the incubation of pre-cultured leukemia K562 cells in the coexistence of CMNPs for a period of time, the CMNPs modified living cells could be rapidly isolated from the medium and immobilized firmly on the electrode surface via a magnetic field, as traced by quartz crystal microbalance. The cyclic voltammetric experiments of...
mesheuropmc: human activities
free text keywords: Chemistry, TP250-261, QD1-999, Industrial electrochemistry
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